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In early 2004, this company set out to find smarter support for their legacy systems, as well as better space, power, and cooling management while improving computer utilization. They looked to virtualization and blades to help achieve these goals.

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Similarly, the individual scales for the various ions must be mutually consistent, ie they must satisfy the relationship between the experimentally measurable mean activity of the electrolyte and the defined activities of the cation and anion in view of Eq (1111) Thus, by using galvanic cells without transport, eg a sodium-ionselective glass electrode and a Cl~-selective electrode in a NaCl solution, a series of a (NaCl) is obtained from which the individual ion activity aNa+ is determined on the basis of the Bates-Guggenheim convention for a cl (page 37) Table 61 lists three such standard solutions, where pNa = -loga Na +, etc 634 Biosensors and other composite systems Devices based on the glass electrode can be used to determine certain gases present in gaseous or liquid phase.

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, a high Tg or the crystallization of the hydrophobic block can render the core of micelle more compact and their dissolution slower) and (2) their sizes can easily be adjusted, by changing the lengths of the blocks, to be in the 20 100 nm range to allow their preferential accumulation in porous cancer tissues through the enhanced permeation and retention mechanism (Haag, 2004) To understand the interest of azobenzene BCP micelles, the question about the utility of light-controllable polymer micelles needs to be answered Using BCP micelles as a nanocarrier of drugs, an effective target-speci c delivery of drugs should consist in three steps The rst step is a stable encapsulation of the drug, meaning that after administration in the body, the BCP micelle protects the drug and prevents it from leaking out quickly..

Such a gas probe consists of a glass electrode covered by a thin film of a plastic material with very small pores,.

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This company didn t have much time to test many different configurations. They started their evaluation of what was available in the market in 2004 when there were not many choices. For their virtualization solution, it came down to a choice between VMware s GSX or ESX solutions. They liked GSX but wanted the broader support afforded by the ESX solution in combination with the PlateSpin PowerConvert and PowerRecon tools.

The second step is a site-speci c transportation of the drug, meaning that the drug-loaded BCP micelle should be selectively captured by the target (pathological sites) The third step is that once arrived on the target the BCP micelle opens the door to allow the drug to be released While the stable encapsulation of drug is crucial for giving the nanocarrier the time required to ferry the drug to the target, it could also render the drug release on the target more dif cult at a later time For each of the three steps, there has been much research effort aimed at developing effective strategies For the stable encapsulation, the crosslinking of BCP micelles is useful to provide the structural integrity and to slow down the leakage of the drug through crosslinked polymer chains (Thurmond et al, 1996).

432 Table 6.1 Conventional standards of ion ;activities. (According to R. G. Bates and M. Alfenaar) Electrolyte NaCl Molality (mol kg"1) 0.001 0.01

For the sitespeci c transportation, the functionalization of the micelle shell with a targeting ligand that can be recognized by a receptor highly exposed by the target remains the most appealing approach (Nasongkla et al, 2006) Finally, to release the drug quickly or in a controlled fashion after the micelle arrives on the target, the micelle should be structurally disrupted To this regard, a large number of BCP micelles have been designed to be able to react to an external stimulus, most of which are sensitive to pH change (Bellomo et al, 2004; Bae et al, 2003; Gillies and Frechet, 2003) This exploits the fact that tumor tissues are known to be slightly acidic (pH B68) and the endosomal and lysosomal compartments of cells have even lower pH (pH B5 6) with respect to the physiological pH 74 (Haag, 2004; Gillies and Frechet, 2003).

With new processor chips, blade servers were delivered with more computing power, and blade usage shifted from scale-out web serving to broader-use servers and to consolidation of distributed servers into blade server farms. The ability to consolidate in a small space using high-density computing was crucial to the early value proposition. Fairly quickly, however, IT also saw that the architecture of blade server systems offered significant reductions in complexity and improvements in manageability. IT continued to make progress with consolidation and started implementing larger blade farms. It became evident that there were issues with power and cooling. Vendors such as Liebert and American Power Conversion (APC) became important players in the blade space, offering products and partnerships to help with power and cooling in the data center. It wasn t long before

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